Genicular Artery Embolization (GAE) is a minimally invasive, image-guided procedure designed to relieve chronic knee pain caused by osteoarthritis. It is an innovative alternative for patients who have not found relief with conservative treatments and want to avoid or delay knee replacement surgery.
What Is GAE?
Genicular Artery Embolization works by reducing abnormal inflammation in the knee joint. In osteoarthritis, tiny blood vessels (genicular arteries) can become enlarged and contribute to ongoing inflammation and pain.
During GAE, a specialized physician uses advanced imaging to guide a small catheter into the arteries supplying the knee. Tiny particles are then injected to selectively block these abnormal vessels, reducing inflammation and significantly decreasing pain.

Benefits of GAE
- Minimally invasive (no large incisions)
- Performed under local anesthesia
- Outpatient procedure
- Minimal downtime
- Faster recovery compared to surgery
- Significant reduction in pain and improved mobility
- Can delay or potentially avoid knee replacement
GAE may be appropriate for patients who:
- Have mild to moderate knee osteoarthritis
- Experience chronic knee pain that limits daily activities
- Have not responded well to physical therapy, medications, or injections
- Are not ready for knee replacement surgery
- Are not ideal surgical candidates due to other health conditions
A comprehensive evaluation and imaging studies help determine if GAE is the right option.
What to Expect
The procedure typically takes about 1–2 hours. Patients usually return home the same day and can resume light activities within a few days. Most patients experience gradual pain relief over several weeks as inflammation decreases.
Is GAE Safe?
GAE has been shown to be a safe and effective treatment for appropriate candidates. As with any medical procedure, there are potential risks, including minor bruising or temporary discomfort at the catheter insertion site. Serious complications are rare when performed by an experienced specialist.

A Modern Approach to Knee Pain Relief
Genicular Artery Embolization represents a breakthrough in the treatment of knee osteoarthritis. By targeting the source of inflammation rather than masking symptoms, GAE offers a promising option for patients seeking long-term relief without major surgery.

